Monday 28 June 2021

Processes for Chromosome Screening of High Quality According to the Quality

 

Before implantation, CCS allows us to examine biopsied cells from an embryo to see whether there are any chromosomal abnormalities. This is done to avoid implanting embryos that will either not result in a healthy pregnancy or will result in miscarriage or diagnosis later in the pregnancy. As a woman gets older, the types of chromosomal mistakes get more complex and common. This explains why older women have lower pregnancy rates and more miscarriages.

Since all women and men have some chromosomally defective sperm and eggs, the likelihood of chromosomal mistakes increases with age and the health history of the parents, particularly the mother's age.

We commonly uncover the cause of "unexplained infertility" in younger women, those under 35 years old, using this technique.

When does it come into play?

Infertility caused by advanced maternal age (more than 35 years), repeated miscarriage, low ovarian capacity in younger women, embryo preservation in gender selection, family building, or other failed reproductive therapies are all treated with comprehensive chromosome screening. Many people may have CCS for personal reasons, such as limiting the option of terminating a baby later in pregnancy due to a chromosomal problem. Finally, a few patients choose CCS to maintain high pregnancy rates while limiting the danger of multiple growth pregnancies by transferring just one embryo at a time.

When Is It Actually Used?

Instead of CCS, PGD may be advised for couples who have or are carriers of a known genetic condition that may cause disability or disease in their children, such as muscular dystrophy or cystic fibrosis; and also for translocations which have been corrected.

Could this therapy differentiate between unaffected and possible carrier embryos? It may help a family to avoid passing on a specific mutation to future generations by identifying unaffected non-carrier embryos.

Conclusion:

The presented complete chromosomal screening technique overcomes many of the difficulties that previously limited aneuploidy screening methods, and may finally allow preimplantation genetic screening to achieve the theoretical benefits.

This high embryo implantation rate achieved is very encouraging, and if confirmed in future research, will be of enormous significance for IVF facilities attempting to reduce the number of embryos transferred or adopt single embryo transfer.

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